Christian Science services were first held in Helensburgh in 1910 when three Christian Scientists met each Sunday morning.   In the afternoon there was a Sunday School for the children of these families.  When war broke out in 1914 two of the families moved away and the services stopped.

In 1924 two students of Christian Science began to read the Bible lessons in their home.  Before long, members of the public who heard of the readings, asked to be allowed to join them to learn about Christian Science.  Permission was gladly given, and these house services gathered strength.  When the house could not accommodate the numbers attending, it was decided to rent a hall.   On Sunday 3rd April 1927, the first service was held in the Masonic Temple.

In 1946 a plot of ground was purchased in West Princes Street on which to build a church.  The building fund grew steadily with contributions from members and friends, and construction work commenced in due course.  The architect was Miss Margaret Brodie of Glasgow, and the builders were a local firm, A Trail and Son.  The stone front was complimented by carved double doors, again the work of a local craftsman, Andrew S MacKenzie.  The church building was completed in April 1959, and the first service was held on Sunday, 3rd May of that year.  Later a building to house the Sunday School was built, and premises for a Christian Science Reading Room were purchased at 106 West Princes Street.